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P2RY1 Polyclonal Antibody

Rabbit Anti-P2RY1 Polyclonal Antibody

Product Specifications

Background

The product of P2RY1 gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.

CAS Number

9007-83-4

Product Name Alternative

P2Y purinoceptor 1; P2Y1; ATP receptor; Purinergic receptor

Gene ID

5028

Accession Number

P47900

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human P2RY1 protein at amino acid sequence of 130-210

Clonality

Polyclonal

Tag

P2RY1

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

41kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of P2RY1 protein

Observed Molecular Weight

41

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

P2Y purinoceptor 1; P2Y1; ATP receptor; Purinergic receptor

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/P47900

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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