P2RX4 Polyclonal Antibody

Rabbit Anti-P2RX4 Polyclonal Antibody

Product Specifications

Background

P2RX4 (Purinergic Receptor P2X 4) is a Protein Coding gene. Diseases associated with P2RX4 include Chronic Pain. Among its related pathways are Calcium signaling pathway and Response to elevated platelet cytosolic Ca2+. The product of P2RX4 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of P2RX4 has the lowest sensitivity for these antagonists.

CAS Number

9007-83-4

Product Name Alternative

P2X purinoceptor 4; P2X4; ATP receptor; Purinergic receptor

Gene ID

5025

Accession Number

Q99571

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human P2RX4 protein at amino acid sequence of 150-230

Clonality

Polyclonal

Tag

P2RX4

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

42kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of P2RX4 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000