NRG4 Polyclonal Antibody

Rabbit Anti-NRG4 Polyclonal Antibody

Product Specifications

Background

NRG4 (Neuregulin 4) is a Protein Coding gene. Among its related pathways are RET signaling and Signaling by ERBB2. GO annotations related to this gene include receptor binding and growth factor activity. Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors (By similarity) .

CAS Number

9007-83-4

Product Name Alternative

Pro-neuregulin-4, membrane-bound isoform; Pro-NRG4

Gene ID

145957

Accession Number

Q8WWG1

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human NRG4 protein at amino acid sequence of 11-60

Clonality

Polyclonal

Tag

NRG4

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

12kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of NRG4 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000