NQO2 Polyclonal Antibody

Rabbit Anti-NQO2 Polyclonal Antibody

Product Specifications

Background

NQO2 (N-Ribosyldihydronicotinamide: quinone Reductase 2) is a Protein Coding gene. Among its related pathways are Metabolism and Cytochrome P450 - arranged by substrate type. NQO2 encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in NQO2 have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

Ribosyldihydronicotinamide dehydrogenase [quinone]; NRH dehydrogenase [quinone] 2; NRH:quinone oxidoreductase 2; Quinone reductase 2; QR2

Gene ID

4835

Accession Number

P16083

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human NQO2 protein at amino acid sequence of 40-120

Clonality

Polyclonal

Tag

NQO2

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

25kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of NQO2 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000