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NPHP1 Polyclonal Antibody

Rabbit Anti-NPHP1 Polyclonal Antibody

Product Specifications

Background

NPHP1 (Nephrocystin 1) is a Protein Coding gene. Diseases associated with NPHP1 include Senior-Loken Syndrome-1 and Nephronophthisis 1, Juvenile. Among its related pathways are Organelle biogenesis and maintenance and Regulation of PLK1 Activity at G2/M Transition. NPHP1 encodes a protein with src homology domain 3 (SH3) patterns. This protein interacts with Crk-associated substrate, and it appears to function in the control of cell division, as well as in cell-cell and cell-matrix adhesion signaling, likely as part of a multifunctional complex localized in actin- and microtubule-based structures.

CAS Number

9007-83-4

Product Name Alternative

Nephrocystin-1; Juvenile nephronophthisis 1 protein

Gene ID

4867

Accession Number

O15259

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human NPHP1 protein at amino acid sequence of 510-590

Clonality

Polyclonal

Tag

NPHP1

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

80kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of NPHP1 protein

Observed Molecular Weight

80

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

Nephrocystin-1; Juvenile nephronophthisis 1 protein

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/O15259

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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