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NMB Polyclonal Antibody

Rabbit Anti-NMB Polyclonal Antibody

Product Specifications

Background

NMB (Neuromedin B) is a Protein Coding gene. Diseases associated with NMB include Gastrinoma and Neuronal Ceroid Lipofuscinosis. Among its related pathways are Signaling by GPCR and RET signaling. NMB encodes a member of the bombesin-like family of neuropeptides, which negatively regulate eating behavior. The encoded protein may regulate colonic smooth muscle contraction through binding to its cognate receptor, the neuromedin B receptor (NMBR) . Polymorphisms of NMB may be associated with hunger, weight gain and obesity. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

Neuromedin-B

Gene ID

4828

Accession Number

P08949

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human NMB protein at amino acid sequence of 20-100

Clonality

Polyclonal

Tag

NMB

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

13kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of NMB protein

Observed Molecular Weight

13

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

Neuromedin-B

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/P08949

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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