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MEISi-1

Product Specifications

UNSPSC Description

MEISi-1 is a homeodomain inhibitor of small molecule MEIS1 protein. MEISi-1 significantly inhibited the activity of luciferase reporter genes containing MEIS binding sites (TGACAG) and induced self-renewal of mouse and human HSCS in vitro and in vivo. MEISi-1 can be used for research in blood diseases, heart regeneration and cancer[1].

Target Antigen

HOXA

Type

Reference compound

Field of Research

Cancer; Cardiovascular Disease; Others

Assay Protocol

https://www.medchemexpress.com/meisi-1.html

Smiles

O=C(NC1=CC=CC(C)=C1C)C2=CC=C(OCC(NCC3=CC=CC=C3)=O)C=C2

Molecular Weight

388.46

References & Citations

[1]Turan R D, et al. Development of Small Molecule MEIS Inhibitors that modulate HSC activity[J]. Scientific reports, 2020, 10(1): 7994.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-134258/MEISi-1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-134258/MEISi-1-SDS-MedChemExpress.pdf

CAS Number

446306-43-0

Available Sizes

Curated Selection

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