MCM9 Polyclonal Antibody

Rabbit Anti-MCM9 Polyclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the mini-chromosome maintenance (MCM) protein family that are essential for the initiation of eukaryotic genome replication. Binding of this protein to chromatin has been shown to be a pre-requisite for recruiting the MCM2-7 helicase to DNA replication origins. This protein also binds, and is a positive regulator of, the chromatin licensing and DNA replication factor 1, CDT1. MCM9 (Minichromosome Maintenance 9 Homologous Recombination Repair Factor) is a Protein Coding gene. Diseases associated with MCM9 include Ovarian Dysgenesis 4 and Fmr1-Related Primary Ovarian Insufficiency. Among its related pathways are Cell cycle.

CAS Number

9007-83-4

Product Name Alternative

DNA helicase MCM9; hMCM9; Mini-chromosome maintenance deficient domain-containing protein 1; Minichromosome maintenance 9

Gene ID

254394

Accession Number

Q9NXL9

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human MCM9 protein

Clonality

Polyclonal

Tag

MCM9

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

125kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of MCM9 protein

Observed Molecular Weight

125

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000