MCF2L Polyclonal Antibody

Rabbit Anti-MCF2L Polyclonal Antibody

Product Specifications

Background

MCF2L encodes a guanine nucleotide exchange factor that interacts specifically with the GTP-bound Rac1 and plays a role in the Rho/Rac signaling pathways. A variant in this gene was associated with osteoarthritis. Alternative splicing results in multiple transcript variants. MCF2L (MCF. Cell Line Derived Transforming Sequence Like) is a Protein Coding gene. Diseases associated with MCF2L include Atypical Autism and Osteoarthritis. Among its related pathways are p75 NTR receptor-mediated signalling and Phospholipase-C Pathway.

CAS Number

9007-83-4

Product Name Alternative

Guanine nucleotide exchange factor DBS; DBL's big sister; MCF2-transforming sequence-like protein

Gene ID

23263

Accession Number

O15068

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human MCF2L protein

Clonality

Polyclonal

Tag

MCF2L

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

125kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of MCF2L protein

Observed Molecular Weight

125

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000