MBP Polyclonal Antibody

Rabbit Anti-MBP Polyclonal Antibody

Product Specifications

Background

MBP (Myelin Basic Protein) is a Protein Coding gene. Diseases associated with MBP include Demyelinating Disease and Central Pontine Myelinolysis. Among its related pathways are IL-1 signaling pathway and Spinal Cord Injury. The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons.

CAS Number

9007-83-4

Product Name Alternative

Myelin basic protein ; MBP; Myelin A1 protein; Myelin membrane encephalitogenic protein

Gene ID

4155

Accession Number

P02686

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from part region of human MBP protein at amino acid sequence of 180-260

Clonality

Polyclonal

Tag

MBP

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

33kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of MBP protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000