MAGD2 Polyclonal Antibody

MAGED2 (MAGE Family Member D2) is a member of the MAGED gene family. The MAGED genes are clustered on chromosome Xp11. MAGED2 is located in Xp11.2, a hot spot for X-linked intellectual disability (XLID) . Mutations in MAGED2 cause a form of transient antenatal Bartter's syndrome. MAGED2 may also be involved in several types of cancer, including breast cancer and melanoma. The protein encoded by MAGED2 is progressively recruited from the cytoplasm to the nucleoplasm during the interphase and after nucleolar stress and is thus thought to play a role in cell cycle regulation. Alternative splicing results in multiple transcript variants.

Melanoma-associated antigen D2; 11B6; Breast cancer-associated gene 1 protein; BCG-1; Hepatocellular carcinoma-associated protein JCL-1; MAGE-D2 antigen

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Melanoma-associated antigen D2; 11B6; Breast cancer-associated gene 1 protein; BCG-1; Hepatocellular carcinoma-associated protein JCL-1; MAGE-D2 antigen