MAGB1 Polyclonal Antibody

MAGEB1 is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. MAGEB1 is localized in the DSS (dosage-sensitive sex reversal) critical region, and expressed in testis and in a significant fraction of tumors of various histological types. MAGEB1 and other MAGEB members are clustered on chromosome Xp22-p21. Multiple alternatively spliced transcript variants encoding the same protein have been found for MAGEB1, however, the full length nature of some variants has not been defined. MAGEB4 is expressed in testis.

Melanoma-associated antigen B1; Cancer/testis antigen 3.1; CT3.1; DSS-AHC critical interval MAGE superfamily 10; DAM10; MAGE-B1 antigen; MAGE-XP antigen

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Melanoma-associated antigen B1; Cancer/testis antigen 3.1; CT3.1; DSS-AHC critical interval MAGE superfamily 10; DAM10; MAGE-B1 antigen; MAGE-XP antigen