MAGA3 Polyclonal Antibody

Rabbit Anti-MAGA3 Polyclonal Antibody

Product Specifications

Background

MAGEA3 (MAGE Family Member A3) is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of MAGEA3 family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. MAGEA3 is a Protein Coding gene. Diseases associated with MAGEA3 include Melanoma and Hepatocellular Carcinoma. An important paralog of this gene is MAGEA6.

CAS Number

9007-83-4

Product Name Alternative

Melanoma-associated antigen 3; Antigen MZ2-D; Cancer/testis antigen 1.3; CT1.3; MAGE-3 antigen

Gene ID

4102

Accession Number

P43357

Reactivity

Human

Immunogen

Synthesized peptide derived from part region of human MAGA3 protein at amino acid sequence of 190-270

Clonality

Polyclonal

Tag

MAGA3

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

34kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of MAGA3 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000