IRK13 Polyclonal Antibody

KCNJ13 (Potassium Voltage-Gated Channel Subfamily J Member 13) is a Protein Coding gene. Diseases associated with KCNJ13 include Snowflake Vitreoretinal Degeneration and Leber Congenital Amaurosis 16. Among its related pathways are Collagen chain trimerization and Dopamine-DARPP32 Feedback onto cAMP Pathway. KCNJ13 encodes a member of the inwardly rectifying potassium channel family of proteins. Members of this family form ion channel pores that allow potassium ions to pass into a cell. The encoded protein belongs to a subfamily of low signal channel conductance proteins that have a low dependence on potassium concentration. Mutations in KCNJ13 are associated with snowflake vitreoretinal degeneration. Alternate splicing results in multiple transcript variants.

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Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000