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INSRR Polyclonal Antibody

Rabbit Anti-INSRR Polyclonal Antibody

Product Specifications

Background

INSRR (Insulin Receptor Related Receptor) is a Protein Coding gene. Diseases associated with INSRR include Regular Astigmatism and Podoconiosis. Among its related pathways are Akt Signaling and Nanog in Mammalian ESC Pluripotency. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is IGF1R. Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.

CAS Number

9007-83-4

Product Name Alternative

IR-related receptor

Gene ID

3645

Accession Number

P14616

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human INSRR protein at amino acid sequence of 80-160

Clonality

Polyclonal

Tag

INSRR

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

142kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of INSRR protein

Observed Molecular Weight

142

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

IR-related receptor

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/P14616

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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