IL-1F6 Polyclonal Antibody

Rabbit Anti-IL-1F6 Polyclonal Antibody

Product Specifications

Background

The protein encoded by IL36A is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of IL36A has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients. IL36A (Interleukin 36, Alpha) is a Protein Coding gene. Diseases associated with IL36A include Psoriasis. Among its related pathways are Toll-Like receptor Signaling Pathways and Cytokine Signaling in Immune system.

CAS Number

9007-83-4

Product Name Alternative

Interleukin-36 alpha; FIL1 epsilon; Interleukin-1 epsilon; IL-1 epsilon; Interleukin-1 family member 6; IL-1F6

Gene ID

27179

Accession Number

Q9UHA7

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human IL-1F6 protein at amino acid sequence of 21-70

Clonality

Polyclonal

Tag

IL-1F6

Applications

IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of IL-1F6

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200; ELISA 1:10000-20000; IF 1:50-200