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IL16 Polyclonal Antibody

Rabbit Anti-IL16 Polyclonal Antibody

Product Specifications

Background

The protein encoded by IL16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of IL16 undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. IL16 (Interleukin 16) is a Protein Coding gene. Diseases associated with IL16 include Whipple Disease and Viral Meningitis. Among its related pathways are Akt Signaling and PEDF Induced Signaling.

CAS Number

9007-83-4

Product Name Alternative

Pro-interleukin-16; Pro-IL16; Pro-IL16

Gene ID

3603

Accession Number

Q14005

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human IL16 protein at amino acid sequence of 900-960

Clonality

Polyclonal

Tag

IL16

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

67kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of IL16

Observed Molecular Weight

67

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:10000-20000

Other Product Names

Pro-interleukin-16; Pro-IL16; Pro-IL16

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q14005

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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