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IFRD1 Polyclonal Antibody

Rabbit Anti-IFRD1 Polyclonal Antibody

Product Specifications

Background

IFRD1 (Interferon Related Developmental Regulator 1) is an immediate early gene that encodes a protein related to interferon-gamma. This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. Mutations in IFRD1 are associated with sensory/motor neuropathy with ataxia. IFRD1 may also be involved in modulating the pathogenesis of cystic fibrosis lung disease. Alternate splicing results in multiple transcript variants. IFRD1 is a Protein Coding gene. Diseases associated with IFRD1 include Spinocerebellar Ataxia 18 and Cystic Fibrosis. Among its related pathways are Hypertrophy Model.

CAS Number

9007-83-4

Product Name Alternative

Interferon-related developmental regulator 1; Nerve growth factor-inducible protein PC4

Gene ID

3475

Accession Number

O00458

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from part region of human IFRD1 protein at amino acid sequence of 280-360

Clonality

Polyclonal

Tag

IFRD1

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

49kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of IFRD1 protein

Observed Molecular Weight

49

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

Interferon-related developmental regulator 1; Nerve growth factor-inducible protein PC4

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/O00458

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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