ID1 Polyclonal Antibody

Rabbit Anti-ID1 Polyclonal Antibody

Product Specifications

Background

ID1 (Inhibitor Of DNA Binding 1, HLH Protein) is a Protein Coding gene. Diseases associated with ID1 include Salivary Gland Cancer and Multicentric Castleman Disease. Among its related pathways are Cellular Senescence (REACTOME) and TGF-B Signaling in Thyroid Cells for Epithelial-Mesenchymal Transition. The protein encoded by ID1 is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for ID1.

CAS Number

9007-83-4

Product Name Alternative

DNA-binding protein inhibitor ID-1; Class B basic helix-loop-helix protein 24; bHLHb24; Inhibitor of DNA binding 1; Inhibitor of differentiation 1

Gene ID

3397

Accession Number

P41134

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from part region of human ID1 protein at amino acid sequence of 30-110

Clonality

Polyclonal

Tag

ID1

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

17kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of ID1 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000