HES5 Polyclonal Antibody

Rabbit Anti-HES5 Polyclonal Antibody

Product Specifications

Background

HES5 (Hes Family BHLH Transcription Factor 5) encodes a member of a family of basic helix-loop-helix transcriptional repressors. The protein product of HES5, which is activated downstream of the Notch pathway, regulates cell differentiation in multiple tissues. Disruptions in the normal expression of HES5 have been associated with developmental diseases and cancer. HES5 is a Protein Coding gene. Diseases associated with HES5 include Valproate Embryopathy, Susceptibility To. Among its related pathways are Signaling by NOTCH1 and NOTCH2 Activation and Transmission of Signal to the Nucleus.

CAS Number

9007-83-4

Product Name Alternative

Transcription factor HES-5; Class B basic helix-loop-helix protein 38; bHLHb38; Hairy and enhancer of split 5

Gene ID

388585

Accession Number

Q5TA89

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from part region of human HES5 protein at amino acid sequence of 10-90

Clonality

Polyclonal

Tag

HES5

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

18kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of HES5 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000