GUC2B Polyclonal Antibody

Rabbit Anti-GUC2B Polyclonal Antibody

Product Specifications

Background

GUCA2B encodes a preproprotein that is proteolytically processed to generate multiple protein products, including uroguanylin, a member of the guanylin family of peptides and an endogenous ligand of the guanylate cyclase-C receptor. Binding of this peptide to its cognate receptor stimulates an increase in cyclic GMP and may regulate salt and water homeostasis in the intestine and kidneys. GUCA2B (Guanylate Cyclase Activator 2B) is a Protein Coding gene. Diseases associated with GUCA2B include Colorectal Cancer. Among its related pathways are Metabolism and Miscellaneous digestion events.

CAS Number

9007-83-4

Product Name Alternative

Guanylate cyclase activator 2B; Guanylate cyclase C-activating peptide 2; Guanylate cyclase C-activating peptide II; GCAP-II; UGN

Gene ID

2981

Accession Number

Q16661

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human GUC2B protein

Clonality

Polyclonal

Tag

GUC2B

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

12kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of GUC2B protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000