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GTR2 Polyclonal Antibody

Rabbit Anti-GTR2 Polyclonal Antibody

Product Specifications

Background

SLC2A2 (Solute Carrier Family 2 Member 2) is a Protein Coding gene. Diseases associated with SLC2A2 include Fanconi-Bickel Syndrome and Diabetes Mellitus, Noninsulin-Dependent. Among its related pathways are Type II diabetes mellitus and Metabolism. SLC2A2 encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. The encoded protein mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in SLC2A2 are associated with susceptibility to diseases, including Fanconi-Bickel syndrome and noninsulin-dependent diabetes mellitus (NIDDM) . Alternative splicing results in multiple transcript variants of SLC2A2.

CAS Number

9007-83-4

Product Name Alternative

Solute carrier family 2, facilitated glucose transporter member 2; Glucose transporter type 2, liver; GLUT-2

Gene ID

6514

Accession Number

P11168

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human GTR2 protein at amino acid sequence of 220-300

Clonality

Polyclonal

Tag

GTR2

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

57kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of GTR2 protein

Observed Molecular Weight

57

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

Solute carrier family 2, facilitated glucose transporter member 2; Glucose transporter type 2, liver; GLUT-2

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/P11168

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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