GRP3 Polyclonal Antibody

Rabbit Anti-GRP3 Polyclonal Antibody

Product Specifications

Background

RASGRP3 (RAS Guanyl Releasing Protein 3) is a Protein Coding gene. Among its related pathways are RET signaling and G-protein signaling TC21 regulation pathway. GO annotations related to RASGRP3 include calcium ion binding and GTPase activator activity. The protein encoded by RASGRP3 is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in RASGRP3 have been associated with systemic lupus erythematosus and several cancers.

CAS Number

9007-83-4

Product Name Alternative

Ras guanyl-releasing protein 3; Calcium and DAG-regulated guanine nucleotide exchange factor III; Guanine nucleotide exchange factor for Rap1

Gene ID

25780

Accession Number

Q8IV61

Reactivity

Human

Immunogen

Synthesized peptide derived from part region of human GRP3 protein at amino acid sequence of 90-170

Clonality

Polyclonal

Tag

GRP3

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

75kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of GRP3 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000