Bethanechol (chloride)

Bethanechol chloride (Carbamyl-β-methylcholine chloride), a parasympathomimetic agent, is a mAChR agonist that exerts its effects via directly stimulating the mAChR (M1, M2, M3, M4, and M5) of the parasympathetic nervous system[1].

Product Specifications

CAS Number

[590-63-6]

Product Name Alternative

Carbamyl-β-methylcholine chloride

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

MAChR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Neurological Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/Bethanechol-chloride.html

Purity

99.56

Solubility

DMSO : 11.11 mg/mL (ultrasonic) |H2O : ≥ 50 mg/mL

Smiles

CC(OC(N)=O)C[N+](C)(C)C.[Cl-]

Molecular Formula

C7H17ClN2O2

Molecular Weight

196.68

Precautions

H302, H315, H319, H335

References & Citations

[1]Inderbir S. Padda, et al. Bethanechol. Treasure Island (FL) : StatPearls Publishing; 2020 Jan-.|[2]M J Fregly, et al. Bethanechol-induced water intake in rats: possible mechanisms of induction. Pharmacol Biochem Behav. 1982 Oct;17 (4) :727-32.|[3]Julia Yuen Hang Liu, et al. Acetylcholine exerts inhibitory and excitatory actions on mouse ileal pacemaker activity: role of muscarinic versus nicotinic receptors. Am J Physiol Gastrointest Liver Physiol. 2020 Jul 1;319 (1) :G97-G107.