CYFP1 Polyclonal Antibody

CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1) encodes a protein that regulates cytoskeletal dynamics and protein translation. The encoded protein is a component of the WAVE regulatory complex (WRC), which promotes actin polymerization. This protein also interacts with the Fragile X mental retardation protein (FMRP) and translation initiation factor 4E to inhibit protein translation. A large chromosomal deletion including CYFIP1 is associated with increased risk of schizophrenia and epilepsy in human patients. Reduced expression of CYFIP1 has been observed in various human cancers and the encoded protein may inhibit tumor invasion. CYFIP1 is a Protein Coding gene. Diseases associated with CYFIP1 include Fragile X Syndrome and Schizophrenia. Among its related pathways are RET signaling and Regulation of actin dynamics for phagocytic cup formation.

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000