CRLF3 Polyclonal Antibody

Rabbit Anti-CRLF3 Polyclonal Antibody

Product Specifications

Background

CRLF3 (Cytokine Receptor Like Factor 3) is a Protein Coding gene. CRLF3 encodes a cytokine receptor-like factor that may negatively regulate cell cycle progression at the G0/G1 phase. Studies of the related rat protein suggest that it may regulate neuronal morphology and synaptic vesicle biogenesis. CRLF3 is one of several genes located in the neurofibromatosis type I tumor suppressor region on the q arm of chromosome 17, a region that is subject to microdeletions, duplications, chromosomal breaks and rearrangements. Alternative splicing ofCRLF3 results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2 and 5.

CAS Number

9007-83-4

Product Name Alternative

Cytokine receptor-like molecule 9; CREME-9; Cytokine receptor-related protein 4; Type I cytokine receptor-like factor p48

Gene ID

51379

Accession Number

Q8IUI8

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human CRLF3 protein at amino acid sequence of 270-350

Clonality

Polyclonal

Tag

CRLF3

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

48kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of CRLF3 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000