CP4F3 Polyclonal Antibody
Rabbit Anti-CP4F3 Polyclonal Antibody
Product Specifications
Background
CYP4F3 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. CYP4F3 is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F8, is approximately 18 kb away. Three transcript variants encoding two different isoforms have been found for CYP4F3.
CAS Number
9007-83-4
Product Name Alternative
20-hydroxyeicosatetraenoic acid synthase; 20-HETE synthase; CYPIVF3; Cytochrome P450 4F3; Cytochrome P450-LTB-omega; Leukotriene-B (4) 20-monooxygenase 2; Leukotriene-B (4) omega-hydroxylase 2
Gene ID
4051
Accession Number
Q08477
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human CP4F3 protein at amino acid sequence of 400-480
Clonality
Polyclonal
Tag
CP4F3
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
57kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of CP4F3 protein
Observed Molecular Weight
57
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
20-hydroxyeicosatetraenoic acid synthase; 20-HETE synthase; CYPIVF3; Cytochrome P450 4F3; Cytochrome P450-LTB-omega; Leukotriene-B (4) 20-monooxygenase 2; Leukotriene-B (4) omega-hydroxylase 2
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q08477
Isotype
Rabbit IgG
Available Sizes
Curated Selection
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