COL8A2 Polyclonal Antibody

Rabbit Anti-COL8A2 Polyclonal Antibody

Product Specifications

Background

COL8A2 (Collagen Type VIII Alpha 2 Chain) is a Protein Coding gene. Diseases associated with COL8A2 include Corneal Dystrophy, Posterior Polymorphous 2 and Corneal Dystrophy, Fuchs Endothelial, 1. Among its related pathways are Phospholipase-C Pathway and Collagen chain trimerization. This gene encodes the alpha 2 chain of type VIII collagen. This protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in COL8A2 are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2.

CAS Number

9007-83-4

Product Name Alternative

Collagen alpha-2 (VIII) chain; Endothelial collagen

Gene ID

1296

Accession Number

P25067

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from part region of human COL8A2 protein at amino acid sequence of 611-660

Clonality

Polyclonal

Tag

COL8A2

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

80kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of COL8A2

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:10000-20000