COE3 Polyclonal Antibody

Rabbit Anti-COE3 Polyclonal Antibody

Product Specifications

Background

EBF3 (Early B-Cell Factor 3) encodes a member of the early B-cell factor (EBF) family of DNA binding transcription factors. EBF proteins are involved in B-cell differentiation, bone development and neurogenesis, and may also function as tumor suppressors. The encoded protein inhibits cell survival through the regulation of genes involved in cell cycle arrest and apoptosis, and aberrant methylation or deletion of EBF3 may play a role in multiple malignancies including glioblastoma multiforme and gastric carcinoma.

CAS Number

9007-83-4

Product Name Alternative

Transcription factor COE3; Early B-cell factor 3; EBF-3; O/E-2; OE-2

Gene ID

253738

Accession Number

Q9H4W6

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human COE3 protein at amino acid sequence of 50-130

Clonality

Polyclonal

Tag

COE3

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

65kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of COE3 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000