CO3 Polyclonal Antibody
Rabbit Anti-CO3 Polyclonal Antibody
Product Specifications
Background
Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. Complement C3 is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in C3 are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.
CAS Number
9007-83-4
Product Name Alternative
Complement C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1
Gene ID
718
Accession Number
P01024
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human CO3 protein
Clonality
Polyclonal
Tag
CO3
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
182kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of CO3 protein
Observed Molecular Weight
182
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Complement C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P01024
Isotype
Rabbit IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6362434-01 0.2 mL
VEGF3, NT (VEGFC, Vascular endothelial growth factor C, Flt4 ligand, Vascular endothelial growth factor-related protein) (APC)
Ask
View Details 
MBS6362434-02 5x 0.2 mL
VEGF3, NT (VEGFC, Vascular endothelial growth factor C, Flt4 ligand, Vascular endothelial growth factor-related protein) (APC)
Ask
View Details 
MBS1046203-01 0.02 mg (E-Coli)
Recombinant Escherichia coli O17:K52:H18 Phosphoribosylformylglycinamidine cyclo-ligase (purM)
Ask
View Details MBS1046203-02 0.02 mg (Yeast)
Recombinant Escherichia coli O17:K52:H18 Phosphoribosylformylglycinamidine cyclo-ligase (purM)
Ask
View Details 
MBS1046203-03 0.1 mg (E-Coli)
Recombinant Escherichia coli O17:K52:H18 Phosphoribosylformylglycinamidine cyclo-ligase (purM)
Ask
View Details MBS1046203-04 0.1 mg (Yeast)
Recombinant Escherichia coli O17:K52:H18 Phosphoribosylformylglycinamidine cyclo-ligase (purM)
Ask
View Details