CLCN5 Polyclonal Antibody

Rabbit Anti-CLCN5 Polyclonal Antibody

Product Specifications

Background

CLCN5 encodes a member of the ClC family of chloride ion channels and ion transporters. The Chloride Voltage-Gated Channel 5 is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.

CAS Number

9007-83-4

Product Name Alternative

H (+) /Cl (-) exchange transporter 5; Chloride channel protein 5; ClC-5; Chloride transporter ClC-5

Gene ID

1184

Accession Number

P51795

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from part region of human CLCN5 protein

Clonality

Polyclonal

Tag

CLCN5

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

82kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of CLCN5 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000