BMP3B Polyclonal Antibody

Rabbit Anti-BMP3B Polyclonal Antibody

Product Specifications

Background

GDF10 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This promotes neural repair after stroke. Additionally, this protein may act as a tumor suppressor and reduced expression of GDF10 is associated with oral cancer.

CAS Number

9007-83-4

Product Name Alternative

Growth/differentiation factor 10; GDF-10; Bone morphogenetic protein 3B; BMP-3B; Bone-inducing protein; BIP

Gene ID

2662

Accession Number

P55107

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human BMP3B protein

Clonality

Polyclonal

Tag

BMP3B

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

52kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of BMP3B protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

Growth/differentiation factor 10; GDF-10; Bone morphogenetic protein 3B; BMP-3B; Bone-inducing protein; BIP

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/P55107

Isotype

Rabbit IgG

Available Sizes

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