AT1A3 Polyclonal Antibody
Rabbit Anti-AT1A3 Polyclonal Antibody
Product Specifications
Background
The protein encoded by ATP1A3 belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta) . The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. ATP1A3 encodes an alpha 3 subunit. Alternatively spliced transcript variants encoding different isoforms have been found for ATP1A3.
CAS Number
9007-83-4
Product Name Alternative
Sodium/potassium-transporting ATPase subunit alpha-3; Na (+) /K (+) ATPase alpha-3 subunit; Na (+) /K (+) ATPase alpha (III) subunit; Sodium pump subunit alpha-3
Gene ID
478
Accession Number
P13637
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human AT1A3 protein at amino acid sequence of 950-1030
Clonality
Polyclonal
Tag
AT1A3
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
111kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of AT1A3 protein
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Sodium/potassium-transporting ATPase subunit alpha-3; Na (+) /K (+) ATPase alpha-3 subunit; Na (+) /K (+) ATPase alpha (III) subunit; Sodium pump subunit alpha-3
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P13637
Isotype
Rabbit IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items