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AKAP4 Polyclonal Antibody

Rabbit Anti-AKAP4 Polyclonal Antibody

Product Specifications

Background

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP4 encodes a member of the AKAP family. The encoded protein is localized to the sperm flagellum and may be involved in the regulation of sperm motility. Alternative splicing of this gene results in two transcript variants encoding different isoforms. AKAP4 (A-Kinase Anchoring Protein 4) is a Protein Coding gene. Diseases associated with AKAP4 include Retinitis Pigmentosa 70. Among its related pathways are Activation of cAMP-Dependent PKA and DAG and IP3 signaling.

CAS Number

9007-83-4

Product Name Alternative

A-kinase anchor protein 4; AKAP-4; A-kinase anchor protein 82 kDa; AKAP 82; hAKAP82; Major sperm fibrous sheath protein; HI; Protein kinase A-anchoring protein 4; PRKA4

Gene ID

8852

Accession Number

Q5JQC9

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human AKAP4 protein at amino acid sequence of 430-510

Clonality

Polyclonal

Tag

AKAP4

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

93kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of AKAP4 protein

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

A-kinase anchor protein 4; AKAP-4; A-kinase anchor protein 82 kDa; AKAP 82; hAKAP82; Major sperm fibrous sheath protein; HI; Protein kinase A-anchoring protein 4; PRKA4

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q5JQC9

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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