MBL-C Polyclonal Antibody

Rabbit Anti-MBL-C Polyclonal Antibody

Product Specifications

Background

MBL2 (mannose binding lectin 2) encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of MBL2 have been associated with susceptibility to autoimmune and infectious diseases.

CAS Number

9007-83-4

Product Name Alternative

MBL2; COLEC1; MBL

Gene ID

4153

Accession Number

P11226

Reactivity

Human, Mouse

Immunogen

Synthetic peptide from human protein at AA range: 21-70

Clonality

Polyclonal

Tag

Mannose-binding lectin (protein C) 2, soluble (opsonic defect)

Applications

WB, IHC

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

27kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous MBL-C protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300