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TASK-1 Polyclonal Antibody

Rabbit Anti-TASK-1 Polyclonal Antibody

Product Specifications

Background

KCNK3 (potassium two pore domain channel subfamily K member 3) encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for KCNK3.

CAS Number

9007-83-4

Product Name Alternative

KCNK3; TASK; TASK1; Potassium channel subfamily K member 3; Acid-sensitive potassium channel protein TASK-1; TWIK-related acid-sensitive K (+) channel 1; Two pore potassium channel KT3.1; Two pore K (+) channel KT3.1

Gene ID

3777

Accession Number

O14649

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the N-terminal region of human TASK-1

Clonality

Polyclonal

Tag

Potassium channel subfamily K member 3

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

53kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

TASK-1 Polyclonal Antibody detects endogenous levels of TASK-1 protein.

Observed Molecular Weight

53

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.

Other Product Names

KCNK3; TASK; TASK1; Potassium channel subfamily K member 3; Acid-sensitive potassium channel protein TASK-1; TWIK-related acid-sensitive K (+) channel 1; Two pore potassium channel KT3.1; Two pore K (+) channel KT3.1

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/O14649

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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