EIF2Bδ Polyclonal Antibody

Rabbit Anti-eIF2Bδ Polyclonal Antibody

Product Specifications

Background

Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by EIF2B4 (eukaryotic translation initiation factor 2B subunit delta) is the fourth, or delta, subunit. Defects in EIF2B4 are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for EIF2B4.

CAS Number

9007-83-4

Product Name Alternative

EIF2B4; EIF2BD; Translation initiation factor eIF-2B subunit delta; eIF-2B GDP-GTP exchange factor subunit delta

Gene ID

8890

Accession Number

Q9UI10

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the Internal region of human eIF2Bδ at AA range: 200-280

Clonality

Polyclonal

Tag

Translation initiation factor eIF-2B subunit delta

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

57kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

EIF2Bδ Polyclonal Antibody detects endogenous levels of eIF2Bδ protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:5000; Not yet tested in other applications.