Cdc14a phosphatase Polyclonal Antibody

Rabbit Anti-Cdc14a phosphatase Polyclonal Antibody

Product Specifications

Background

The protein encoded by CDC14A (cell division cycle 14A) is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of CDC14A results in several transcript variants encoding distinct isoforms.

CAS Number

9007-83-4

Product Name Alternative

CDC14A; Dual specificity protein phosphatase CDC14A; CDC14 cell division cycle 14 homolog A

Gene ID

8556

Accession Number

Q9UNH5

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human Cdc14a phosphatase

Clonality

Polyclonal

Tag

Dual specificity protein phosphatase CDC14A

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

66kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Cdc14a phosphatase Polyclonal Antibody detects endogenous levels of Cdc14a phosphatase protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.