Cdk11A/B Polyclonal Antibody

Rabbit Anti-Cdk11A/B Polyclonal Antibody

Product Specifications

Background

CDK11A (cyclin dependent kinase 11A) encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, CDK11A shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by CDK11A can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

CDK11A; CDC2L2; CDC2L3; PITSLREB; Cyclin-dependent kinase 11A; Cell division cycle 2-like protein kinase 2; Cell division protein kinase 11A; Galactosyltransferase-associated protein kinase p58/GTA; PITSLRE serine/threonine-protein kinase C

Gene ID

728642/984

Accession Number

Q9UQ88/P21127

Reactivity

Human

Immunogen

Synthesized peptide derived from the Internal region of human Cdk11A/B at AA range: 190-270

Clonality

Polyclonal

Tag

Cell division protein kinase 11A

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

90kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Cdk11A/B Polyclonal Antibody detects endogenous levels of Cdk11A/B protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.