CD141 Polyclonal Antibody

Rabbit Anti-CD141 Polyclonal Antibody

Product Specifications

Background

The protein encoded by this intronless gene THBD (thrombomodulin) is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in THBD are a cause of thromboembolic disease, also known as inherited thrombophilia.

CAS Number

9007-83-4

Product Name Alternative

THBD; THRM; Thrombomodulin; TM; Fetomodulin; CD antigen CD141

Gene ID

7056

Accession Number

P07204

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the C-terminal region of human CD141 at AA range: 500-580

Clonality

Polyclonal

Tag

Thrombomodulin

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

100kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

CD141 Polyclonal Antibody detects endogenous levels of CD141 protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:5000; Not yet tested in other applications.