SRY Polyclonal Antibody

Rabbit Anti-SRY Polyclonal Antibody

Product Specifications

Background

This intronless gene SRY (sex determining region Y) encodes a transcription factor that is a member of the high mobility group (HMG) -box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in SRY give rise to XY females with gonadal dysgenesis (Swyer syndrome) ; translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.

CAS Number

9007-83-4

Product Name Alternative

SRY; TDF; Sex-determining region Y protein; Testis-determining factor

Gene ID

6736

Accession Number

Q05066

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human SRY at AA range: 30-110

Clonality

Polyclonal

Tag

Sex-determining region Y protein

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

37kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

SRY Polyclonal Antibody detects endogenous levels of SRY protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200