DUS2L Polyclonal Antibody

Rabbit Anti-DUS2L Polyclonal Antibody

Product Specifications

Background

DUS2 (dihydrouridine synthase 2) encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. DUS2 has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for DUS2.

CAS Number

9007-83-4

Product Name Alternative

DUS2L; DUS2; tRNA-dihydrouridine (20) synthase [NAD (P) +]-like; Up-regulated in lung cancer protein 8; URLC8; tRNA-dihydrouridine synthase 2-like; hDUS2

Gene ID

54920

Accession Number

Q9NX74

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the C-terminal region of human DUS2L at AA range: 390-470

Clonality

Polyclonal

Tag

TRNA-dihydrouridine (20) synthase [NAD (P) +]-like

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

55kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

DUS2L Polyclonal Antibody detects endogenous levels of DUS2L protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200

Other Product Names

DUS2L; DUS2; tRNA-dihydrouridine (20) synthase [NAD (P) +]-like; Up-regulated in lung cancer protein 8; URLC8; tRNA-dihydrouridine synthase 2-like; hDUS2