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E-Ras Polyclonal Antibody

Rabbit Anti-E-Ras Polyclonal Antibody

Product Specifications

Background

ERAS encodes a constitutively active member of the small GTPase Ras protein family. The ES cell expressed Ras activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. ERAS may be involved in cancer and chemotherapy resistance.

CAS Number

9007-83-4

Product Name Alternative

ERAS; HRAS2; HRASP; GTPase ERas; E-Ras; Embryonic stem cell-expressed Ras

Gene ID

3266

Accession Number

Q7Z444

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the C-terminal region of human E-Ras at AA rangle: 160-240

Clonality

Polyclonal

Tag

GTPase Eras

Applications

WB, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

25kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

E-Ras Polyclonal Antibody detects endogenous levels of E-Ras protein.

Product Datasheet

https://www.abbkine.com/datasheet/ABP54774.pdf

Observed Molecular Weight

25

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.

Other Product Names

ERAS; HRAS2; HRASP; GTPase ERas; E-Ras; Embryonic stem cell-expressed Ras

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q7Z444

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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