GPR124 Polyclonal Antibody

Rabbit Anti-GPR124 Polyclonal Antibody

Product Specifications

Background

ADGRA2 (Adhesion G Protein-Coupled Receptor A2) is a Protein Coding gene. Among its related pathways are Integrins in angiogenesis. GO annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is ADGRA1. ndothelial receptor which functions as a WNT7-specific coactivator of canonical Wnt signaling (By similarity) . Required for normal endothelial cell sprouting and migration in the forebrain and neural tube (By similarity) . Has a major role in establishing the blood-brain barrier (By similarity) . Binds to the glycosaminoglycans heparin, heparin sulfate, chondroitin sulfate and dermatan sulfate (PubMed: 16982628) .

CAS Number

9007-83-4

Product Name Alternative

GPR124; KIAA1531; TEM5; G-protein coupled receptor 124; Tumor endothelial marker 5

Gene ID

25960

Accession Number

Q96PE1

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from the C-terminal region of human GPR124 at AA rangle: 1120-1200

Clonality

Polyclonal

Tag

G-protein coupled receptor 124

Applications

WB, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

145kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

GPR124 Polyclonal Antibody detects endogenous levels of GPR124 protein.

Observed Molecular Weight

145

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.