TEL Polyclonal Antibody

Rabbit Anti-TEL Polyclonal Antibody

Product Specifications

Background

ETV6 encodes an ETS family transcription factor. The product of ETV6 contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. ETV6 is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.

CAS Number

9007-83-4

Product Name Alternative

ETV6; TEL; TEL1; Transcription factor ETV6; ETS translocation variant 6; ETS-related protein Tel1; Tel

Gene ID

2120

Accession Number

P41212

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from human TEL around the non-phosphorylation site of S257

Clonality

Polyclonal

Tag

Transcription factor ETV6

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

55kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

TEL Polyclonal Antibody detects endogenous levels of TEL protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.