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CB1 Polyclonal Antibody

Rabbit Anti-CB1 Polyclonal Antibody

Product Specifications

Background

CNR1 encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.

CAS Number

9007-83-4

Product Name Alternative

CNR1; CNR; Cannabinoid receptor 1; CB-R; CB1; CANN6

Gene ID

1268

Accession Number

P21554

Reactivity

Human, Mouse, Rat, Monkey

Immunogen

Synthesized peptide derived from the Internal region of human CB1 at AA rangle: 120-200

Clonality

Polyclonal

Tag

Cannabinoid receptor 1

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

53kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

CB1 Polyclonal Antibody detects endogenous levels of CB1 protein.

Observed Molecular Weight

53

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.

Other Product Names

CNR1; CNR; Cannabinoid receptor 1; CB-R; CB1; CANN6

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/P21554

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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