CLN5 Polyclonal Antibody

Rabbit Anti-CLN5 Polyclonal Antibody

Product Specifications

Background

CLN5 is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL) . Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.

CAS Number

9007-83-4

Product Name Alternative

CLN5; Ceroid-lipofuscinosis neuronal protein 5; Protein CLN5

Gene ID

1203

Accession Number

O75503

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the Internal region of human CLN5 at AA rangle: 140-220

Clonality

Polyclonal

Tag

Ceroid-lipofuscinosis neuronal protein 5

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

48kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

CLN5 Polyclonal Antibody detects endogenous levels of CLN5 protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.