AID Polyclonal Antibody

Rabbit Anti-AID Polyclonal Antibody

Product Specifications

Background

AICDA encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. Activation-induced cytidine deaminase is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2) .

CAS Number

9007-83-4

Product Name Alternative

AICDA; AID; Activation-induced cytidine deaminase; Cytidine aminohydrolase

Gene ID

57379

Accession Number

Q9GZX7

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the Internal region of human AID

Clonality

Polyclonal

Tag

Activation-induced cytidine deaminase

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

24kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

AID Polyclonal Antibody detects endogenous levels of AID protein.

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:10000; IF 1:50-200