Jagged1 Polyclonal Antibody

Rabbit Anti-Jagged1 Polyclonal Antibody

Product Specifications

Background

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

CAS Number

9007-83-4

Product Name Alternative

JAG1; JAGL1; Protein jagged-1; Jagged1; hJ1; CD339

Gene ID

182

Accession Number

P78504

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the Internal region of human Jagged1

Clonality

Polyclonal

Tag

Protein jagged-1

Applications

IF, WB, IHC, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

140kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

Jagged1 Polyclonal Antibody detects endogenous levels of Jagged1 protein.

Observed Molecular Weight

140

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:50-200; WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:20000; Not yet tested in other applications