NUMB Polyclonal Antibody
Rabbit Anti-NUMB Polyclonal Antibody
Product Specifications
Background
Protein numb homolog encoded by NUMB plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Product Name Alternative
NUMB; Protein numb homolog; h-Numb; Protein S171
Gene ID
8650
Accession Number
P49757
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human NUMB
Clonality
Polyclonal
Tag
Protein numb homolog
Applications
WB, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
70kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
NUMB Polyclonal Antibody detects endogenous levels of NUMB protein.
Observed Molecular Weight
70
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IF/ICC1:100-500; ELISA 1:5000-20000
Other Product Names
NUMB; Protein numb homolog; h-Numb; Protein S171
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P49757
Isotype
Rabbit IgG
Available Sizes
Curated Selection
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